How do you titrate a milrinone?
50 mcg/kg IV load, then 0.33 to 0.5 mcg/kg/minute continuous IV infusion, initially. Titrate by 0.33 mcg/kg/minute every 2 hours until clinical response is attained. Max: 1 mcg/kg/minute. Avoid loading dose to minimize the risk of hypotension.
How do you give milrinone infusion?
Adults: Milrinone Injection should be given as a loading dose of 50μg/kg administered over a period of 10 minutes usually followed by a continuous infusion at a dosage titrated between 0.375μg/kg/min and 0.75μg/kg/min according to haemodynamic and clinical response, but should not exceed 1.13mg/kg/day total dose.
Can Dilaudid be given IVP?
DILAUDID INJECTION may be given intravenously, but the injection should be given very slowly. Rapid intravenous injection of opioid analgesics increases the possibility of side effects such as hypotension and respiratory depression.
What is a milrinone drip used for?
Milrinone is a medication indicated for cardiac support in patients with acute heart failure, pulmonary hypertension, or chronic heart failure.
Does milrinone need a central line?
Adult Critical Care Protocol: May be administered by IV infusion by a nurse in Adult Critical Care. Each loading dose and infusion rate must be ordered by physician; nurses are not approved to titrate milrinone. Must be administered via central venous access device.
How fast can you wean milrinone?
Weaning: The infusion should be weaned slowly (2–4-hourly), monitoring for clinical signs of inadequate cardiac output.
How is milrinone administered at home?
Milrinone is given as a continuous infusion. When given in the home setting, you and a willing caregiver who is living in the home, must learn how to manage the infusion (change the medication bag, troubleshoot the IV pump, and identify when a problem is occurring).
How do you give IV hydromorphone?
Intravenous Administration: The initial starting dose is 0.2 to 1 mg every 2 to 3 hours. Intravenous administration should be given slowly, over at least 2 to 3 minutes, depending on the dose. The initial dose should be reduced in the elderly or debilitated and may be lowered to 0.2 mg.
How do you give a Hydromorphone Injection?
- Adults—At first, 1 to 2 milligrams (mg) injected under the skin or into one of your muscles every 2 to 3 hours as needed. Your doctor may adjust your dose as needed.
- Children—Use and dose must be determined by your doctor.
Does milrinone cause Vtach?
In 91% of the patients, 1 week of oral milrinone therapy was associated with no significant change (85%) or a significant decrease (6%) in the density of ventricular couplets and frequency of ventricular tachycardia.
Can you be weaned off milrinone?
We report the clinical course of a patient with severe congestive heart failure, whom we treated successfully with continuous milrinone infusions as an outpatient and later were able to wean off of milrinone after upward titration of high-dose carvedilol.
What happens if you stop milrinone?
If your milrinone stops infusing it is possible that you will experience sudden and severe symptoms of heart failure. If you are not able to promptly restart the infusion, you or your caregiver must initiate your community’s Emergency Medical System by calling 911 immediately.