Is a 4 cm thyroid nodule considered large?
In previous studies, the presence of thyroid nodules larger than 4 cm with cytologic atypia, follicular lesions, or suspicious findings is considered an independent indication for thyroidectomy, regardless of FNAB results.
Can a 4 cm thyroid nodule be benign?
Another study of 155 patients, who underwent thyroidectomy for thyroid nodules 4 cm or larger, found that 7.7% of nodules reported as benign on FNAB were found to be malignant on final pathology [14]. Contrary to our study, the risk of malignancy in their study was 27.3% among patients with nondiagnostic FNA cytology.
At what size do thyroid nodules need to be removed?
Previous studies had shown that between 11- 20% of cancerous nodules ≥ 4 cm may be misclassified as benign (false negative) and this has led to recommendations that all nodules > 4 cm should be removed.
What size thyroid nodule is worrisome?
Nodular size of 1 – 1.9 cm was more prevalent among cancer patients than in benign cases (p<0.001). The highest malignancy risk was observed in nodules <2 cm and no increase in malignancy risk for nodules >2 cm.
What is Category 4 thyroid nodule?
Bethesda category IV nodules are described as follicular neoplasm or suspicious for follicular neoplasm (FN/SFN).
What is a Grade 4 thyroid nodule?
ACR TI-RADS Grade 4, where the benign and malignant nodules can easily overlap, in this modified TI-RADS, was further divided into grade 4a, 4b, and 4c, as shown in Figure 1. In each patient with more than one nodule, only the highest grade of nodules was registered and monitored.
What size nodule should be biopsied?
According to the Society of Radiologists in Ultrasound, biopsy should be performed on a nodule 1 cm in diameter or larger with microcalcifications, 1.5 cm in diameter or larger that is solid or has coarse calcifications, and 2 cm in diameter or larger that has mixed solid and cystic components, and a nodule that has …
How serious is a TR4 thyroid nodule?
“Moderately suspicious” or TR4 nodules are 4 to 6 points, and TR5 nodules or “highly suspicious” have sums of 7 points or more. For TR4 nodules, the guidelines recommend fine-needle aspiration if the nodule is 1.5cm or larger, and follow-ups if larger than 1cm.
Is a 5mm thyroid nodule serious?
In thyroid nodules ≤ 5 mm found on US, US-FNA could be recommended in cases of increased size during US follow-up if lateral LNM was not found because a delay in surgery did not impact cancer recurrence and mortality.