What are the three variant of frontotemporal dementia?
Three main clinical variants are recognized: Behavioral variant (bv-FTD), Semantic dementia (SD), and Progressive nonfluent aphasia (PNFA). However, logopenic/phonological (LPA) variant has been recently described, showing a distinctive pattern of brain atrophy and often associated to Alzheimer’s disease pathology.
What is vascular frontotemporal dementia?
Frontotemporal dementia (FTD), a common cause of dementia, is a group of disorders that occur when nerve cells in the frontal and temporal lobes of the brain are lost. This causes the lobes to shrink. FTD can affect behavior, personality, language, and movement.
What is the life expectancy of someone with frontotemporal dementia?
The rate at which FTD progresses varies greatly, with life expectancy ranging from less than two years to 10 years or more. Research shows that on average, people live for about six to eight years after the start of symptoms but this varies widely.
What is the main cause of frontotemporal dementia?
Frontotemporal dementia is caused by clumps of abnormal protein forming inside brain cells. These are thought to damage the cells and stop them working properly. The proteins mainly build up in the frontal and temporal lobes of the brain at the front and sides.
Does FTD show up on MRI?
Brain imaging is indicated in all individuals with symptoms of FTD to rule out structural causes. MRI scanning will identify small vessel ischemia, subdural hematomas, strategically placed tumors and hydrocephalus. Additionally, the pattern of brain atrophy can support the diagnosis.
How early can FTD start?
But frontotemporal dementia tends to occur at a younger age than does Alzheimer’s disease. Frontotemporal dementia often begins between the ages of 40 and 65 but occurs later in life as well.
What is a common treatment for frontotemporal dementia?
Antidepressants. Some types of antidepressants, such as trazodone, may reduce the behavioral problems associated with frontotemporal dementia. Selective serotonin reuptake inhibitors (SSRIs) — such as citalopram (Celexa), paroxetine (Paxil) or sertraline (Zoloft) — also have been effective in some people.