Meropenem has excellent activity against a broad range of bacteria including many Gram-positive and Gram-negative pathogens, including many potentially resistant strains such as Pseudomonas aeruginosa, as well as anaerobic organisms (Wiseman et al 1995; Fish and Singletary 1997).
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What organisms does meropenem cover?
Meropenem has excellent activity against a broad range of bacteria including many Gram-positive and Gram-negative pathogens, including many potentially resistant strains such as Pseudomonas aeruginosa, as well as anaerobic organisms (Wiseman et al 1995; Fish and Singletary 1997).
What is the difference between meropenem and ceftriaxone?
Meropenem had significantly superior killing activity to that of ceftriaxone used alone. Nairn et al. reported similar results in experimental pneumococcal meningitis with resistant strains (22). The bactericidal activity of meropenem was similar to that of ceftriaxone-vancomycin.
Can meropenem and ceftriaxone combine?
A novel combination that includes ceftriaxone, sulbactam and disodium EDTA, or CSE, was noninferior to meropenem for the treatment of complicated UTIs, or cUTIs, caused by extended-spectrum beta-lactamase-producing, or ESBL-producing, gram-negative bacteria, according to results from the phase 3 PLEA trial.
What organisms does ceftriaxone cover?
Ceftriaxone is a broad-spectrum β-lactam (cephalosporin/cephamycin) antibiotic that displays in vitro activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria.
What organisms does doxycycline cover?
Doxycycline has a broad spectrum of activity and is effective against gram-positive and gram-negative, aerobic and anaerobic bacteria, spirochetes, and mycoplasma.
Is ceftriaxone broad spectrum antibiotic?
Ceftriaxone: a beta-lactamase-stable, broad-spectrum cephalosporin with an extended half-life.
Which is better meropenem or Piptaz?
Findings In this noninferiority randomized clinical trial that included 391 patients with E coli or K pneumoniae bloodstream infection and ceftriaxone resistance, the 30-day mortality rate for patients treated with piperacillin-tazobactam compared with meropenem was 12.3% vs 3.7%, respectively.
Does meropenem cover Klebsiella pneumoniae?
The novel carbapenem/beta-lactamase inhibitor meropenem/vaborbactam (Vabomere) specifically addresses carbapenem-resistant Enterobacteriaceae (CRE) (eg, E coli, K pneumoniae) by inhibiting the production of enzymes that block carbapenem antibiotics, one of the more powerful classes of drugs in the antibiotic arsenal.
What is meropenem injection?
Meropenem injection is used to treat infections caused by bacteria. It works by killing the bacteria or preventing their growth. This medicine will not work for colds, flu, or other virus infections. This medicine is to be given only by or under the direct supervision of your doctor.
What is the action of meropenem?
Meropenem is used to treat a wide variety of bacterial infections. This medication is known as a carbapenem-type antibiotic. It works by stopping the growth of bacteria.
Can ceftriaxone treat Staphylococcus?
Despite these microbiologic and pharmacokinetic concerns, ceftriaxone has been successful in the treatment of methicillin-sensitive Staphylococcus aureus (MSSA) infections including cases of bone and joint infection (BJI).
How is doxycycline dosed?
Adults—100 milligrams (mg) every 12 hours on the first day, then 100 mg once a day or 50 to 100 mg every 12 hours. Children 8 years of age or older weighing 45 kilograms (kg) or more—100 mg every 12 hours on the first day, then 100 mg once a day or 50 to 100 mg every 12 hours.
What type of drug is meropenem?
KEY POINTS Meropenem (Merrem) is an injectable carbapenem and beta-lactam antibiotic that interferes with bacterial cell wall synthesis in sensitive organisms Has activity versus a wide array of organisms, including multi-drug resistant Acinetobacter baumannii, Pseudomonas aeruginosa and Klebsiella pneumoniae DOES NOT cover MRSA or VRE
Is meropenem effective for the treatment of bacterial meningitis?
A randomised comparison of meropenem with cefotaxime or ceftriaxone for the treatment of bacterial meningitis in adults. Meropenem Meningitis Study Group Third-generation cephalosporins are presently the agents of choice for the empirical antimicrobial therapy of bacterial meningitis.
Is Merrem a carbapenem?
Meropenem (Merrem) is an injectable carbapenem and beta-lactam antibiotic that interferes with bacterial cell wall synthesis in sensitive organisms. Has activity versus a wide array of organisms, including multi-drug resistant Acinetobacter baumannii, Pseudomonas aeruginosa and Klebsiella pneumoniae. DOES NOT cover MRSA or VRE.
What is Merrem (Merrem)?
Meropenem (Merrem) is an injectable carbapenem and beta-lactam antibiotic that interferes with bacterial cell wall synthesis in sensitive organisms Has activity versus a wide array of organisms, including multi-drug resistant Acinetobacter baumannii, Pseudomonas aeruginosa and Klebsiella pneumoniae DOES NOT cover MRSA or VRE