Which are inotropic drugs?
Inotropic Agents
- amrinone.
- digoxin.
- dobutamine.
- dopamine.
- inamrinone.
- Intropin.
- Lanoxin.
- milrinone.
What are inotropic drugs and examples?
Examples of positive inotropic agents include:
- Digoxin.
- Berberine.
- Calcium.
- Calcium sensitisers. Levosimendan.
- Catecholamines. Dopamine. Dobutamine. Dopexamine. Adrenaline (epinephrine) Isoproterenol (isoprenaline)
- Angiotensin II.
- Eicosanoids. Prostaglandins.
- Phosphodiesterase inhibitors. Enoximone. Milrinone. Amrinone. Theophylline.
What are names of inotropes?
WHAT ARE DRUG NAMES OF INOTROPIC AGENTS?
- Amrinone.
- Digoxin.
- Dobutamine.
- Dopamine.
- Inamrinone.
- Intropin.
- Lanoxin.
- Milrinone.
What drugs are positive inotropes?
Positive inotropic medications include cardiac glycosides, like digoxin; beta agonists, like dobutamine; and phosphodiesterase inhibitors, like milrinone. They are used in conditions where the heart can’t pump enough blood to the body’s tissues, like in systolic heart failure.
Is hydralazine an inotrope?
Hydralazine, because of its inotropic properties and ability to augment sympathetic tone, can increase myocardial oxygen consumption more than the accompanying rise in coronary blood flow and myocardial perfusion.
Is amiodarone inotropic?
In addition to the superior efficacy compared with most other antiarrhythmic drugs, amiodarone has very little negative inotropic activity and a low rate of ventricular proarrhythmia, making it advantageous for use in patients with heart failure [1].
Is amiodarone an inotrope?
In conclusion, amiodarone exerts acute electrophysiological and inotropic effects in vitro. The class III antiarrhythmic action of amiodarone is linked with positive inotropy.
Is Nitroglycerin an inotrope?
The positive inotropic effect of nitroglycerin is associated with the two processes, catecholamine release from sympathetic nerve terminals and blockade of phosphodiesterase activity. The positive chronotropic effect arises from the indirect sympathomimetic properties of nitroglycerin.
Is digoxin inotropic?
Digoxin is one of the positive inotropic agents which improves hemodynamics and does not have a deteriorating effect on blood pressure or heart rate [9].
Is hydralazine a negative Inotrope?
The effects of hydralazine (HYD) on heart rate and blood pressure in the intact dog and on atrial rate and contractile force in the isolated atrium were investigated. HYD (0.1-1 mg) injected into the sinus node artery produced double peaked positive inotropic and negative chronotropic effects in a dose-related manner.
How is hydralazine metabolized?
Hydralazine is metabolized primarily by N-acetylation in the liver. It also forms hydrazones (i.e., the acetone hydrazone and the pyruvic acid hydrazone), which may contribute to the BP-lowering effect.
What is amiodarone 400mg used for?
This medication is used to treat certain types of serious (possibly fatal) irregular heartbeat (such as persistent ventricular fibrillation/tachycardia). It is used to restore normal heart rhythm and maintain a regular, steady heartbeat. Amiodarone is known as an anti-arrhythmic drug.
What are some examples of an inotropic medication?
Cholesterol-lowering medicines
Is digoxin a positive inotrope?
Digoxin remains the only (albeit weak) positive inotrope that is valuable in the management of chronic heart failure. βAdrenoceptor blockers have traditionally been avoided in patients with heart failure due to their negative inotropic effects.
Is digoxin A dromotropic chronotropic or inotropic agent?
Digoxin is an inotropic drug that helps the heart contract forcefully. On the other hand, digoxin is also a negative chronotropic drug. To elaborate further, digoxin is an inotropic drug because it causes the forceful contraction to help the atriums squeeze out blood efficiently.
Is amiodarone a positive or negative inotrope?
In conclusion, amiodarone exerts acute electrophysiological and inotropic effects in vitro. The class III antiarrhythmic action of amiodarone is linked with positive inotropy.